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Use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in context of COVID

Jiuyang Xu, Chaolin Huang, Guohui Fan, Zhibo Liu, Lianhan Shang, Fei Zhou, Yeming Wang, Jiapei Yu, Luning Yang, Ke Xie, Zhisheng Huang, Lixue Huang, Xiaoying Gu, Hui Li, Yi Zhang, Yimin Wang, Frederick G. Hayden, Peter W. Horby, Bin Cao, Chen Wang

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 601-612 doi: 10.1007/s11684-020-0800-y

Abstract: The possible effects of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockersOur findings confirm the lack of an association between chronic receipt of renin-angiotensin system antagonists

Keywords： COVID-19     SARS-CoV-2     hypertension     angiotensin-converting enzyme inhibitor     angiotensin II receptor blocker    

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Strategies and Advances in Combating COVID-19 in China Review

Wei Liu, Wei-Jie Guan, Nan-Shan Zhong

Engineering 2020, Volume 6, Issue 10,   Pages 1076-1084 doi: 10.1016/j.eng.2020.10.003

Abstract:

Coronavirus disease 2019 (COVID-19)—the third in a series of coronavirus infections—has caused a global public health event in the 21st century, resulting in substantial global morbidity and mortality. Building on its legacy of managing severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), China has played a key role in the scientific community by revealing the viral transmission routes and clinical characteristics of COVID-19 and developing novel therapeutic interventions and vaccines. Despite these rapid scientific and technological advances, uncertainties remain in tracing the original sources of infection, determining the routes of transmission and pathogenesis, and addressing the lack of targeted clinical management of COVID-19. Here, we summarize the major COVID-19 research advances in China in order to provide useful information for global pandemic control.

Keywords： Coronavirus disease 2019     Angiotensin-converting enzyme     Immune response     Inflammation     Clinical characteristics    

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Renin--angiotensin system inhibitor is associated with the reduced risk of all-cause mortality in COVID

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 102-110 doi: 10.1007/s11684-021-0850-9

Abstract: retrospectively enrolled from January 2020 to March 2020 to investigate the association between the use of renin–angiotensinsystem inhibitor (RAS-I) and the outcome of this disease.Associations between the use of RAS-I (angiotensin-converting enzyme inhibitor (ACEI) or angiotensin

Keywords： COVID-19     RAS inhibitor     hypertension     all-cause mortality    

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Influence of β-elemene on the secretion of angiotensin II and expression of AT1R in hepatic stellate

Ling YANG, Rui ZHU, Qingjing ZHU, Dan DAN, Jin YE, Keshu XU, Xiaohua HOU

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 36-40 doi: 10.1007/s11684-009-0020-y

Abstract: This study aims to investigate the influence of β-elemene on the secretion of angiotensin II (ANG II)and the expression of angiotensin receptor type 1 (AT1R) in hepatic stellate cells (HSCs)

Keywords： liver cirrhosis     beta-elemene     hepatic stellate cells     angiotensin II     receptor     angiotensin     type 1    

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Designer enzyme for green materials innovation: Lactate-polymerizing enzyme as a key catalyst

Seiichi Taguchi

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 139-142 doi: 10.1007/s11705-017-1636-0

Abstract: In this commentary, discovery story of a “lactate-polymerizing enzyme” (LPE)?and LPE-based?

Keywords： synthetic biology     enzyme evolutionary engineering     polyhydroxyalkanoate    

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Power to gas: addressing renewable curtailment by converting to hydrogen

Xiaohe YAN, Xin ZHANG, Chenghong GU, Furong LI

Frontiers in Energy 2018, Volume 12, Issue 4,   Pages 560-568 doi: 10.1007/s11708-018-0588-5

Abstract: From demonstration, it is reasonable to conclude that converting excessive wind power into hydrogen to

Keywords： blending hydrogen     cost-benefit analysis     electrolysis     wind curtailment    

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Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 19-24 doi: 10.1007/s11684-008-0005-2

Abstract: The aim of this study is to investigate the effects of RNA interference (RNAi) targeting angiotensin

Keywords： therapy     Sprague     administration     cardiac hypertrophy     valsartan    

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Influence of glucose feeding on the ligninolytic enzyme production of the white-rot fungus Phanerochaete

ZHOU Xiaoyan, WEN Xianghua, FENG Yan

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 1,   Pages 89-94 doi: 10.1007/s11783-007-0017-1

Abstract: The present work studied the influence of glucose feeding on the ligninolytic enzyme production of inthe first day of the culture (24 h after the inoculation) stimulated both fungal biomass growth and enzymeof MnP activity were 2.7 and 3 times greater compared to the contrast culture, respectively, and the enzyme

Keywords： enzyme production     fed-batch culture     nitrogen-limited     inoculation     mmol/L    

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Diffusion process in enzyme–metal hybrid catalysts

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 6,   Pages 921-929 doi: 10.1007/s11705-022-2144-4

Abstract: Enzyme–metal hybrid catalysts bridge the gap between enzymatic and heterogeneous catalysis, which isPrevious studies have demonstrated that the enzyme–metal hybrid catalysts exhibited considerably highercatalytic efficiency in cascade reactions, compared with that of the combination of separated enzymeHere, we investigated the diffusion process in enzyme–metal hybrid catalysts using Pd/lipase-Pluronicand metal active sites, which provides a theoretical foundation for the rational design of enzyme–metal

Keywords： enzyme–metal hybrid catalyst     internal diffusion     proximity effect     kinetic model    

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Detection of Escherichia coli in wastewater based on enzyme immunoassay

XI Haiyan, CAI Qiang, HE Miao, SHI Hanchang

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 3,   Pages 381-384 doi: 10.1007/s11783-007-0065-6

Abstract: This research describes a fast detection method on the basis of enzyme-linked immunosorbent assay (ELISA

Keywords： conventional     sandwich     pretreatment     enzyme-linked immunosorbent     detection    

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Enzyme@bismuth-ellagic acid: a versatile platform for enzyme immobilization with enhanced acid-base stability

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 6,   Pages 784-794 doi: 10.1007/s11705-022-2278-4

Abstract: In situ encapsulation is an effective way to synthesize enzyme@metal–organic framework biocatalysts

Keywords： bismuth-ellagic acid     in situ encapsulation     enzyme@MOF biocomposites    

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Soil enzyme activities and their indication for fertility of urban forest soil

SHAN Qihua, YU Yuanchun, ZHANG Jinchi, YU Jian

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 2,   Pages 218-223 doi: 10.1007/s11783-008-0037-5

Abstract: To reveal the biological characteristics of urban forest soil and the effects of soil enzyme on soilfertility as well as the correlation between physicochemical properties and enzyme activities, 44 urbanBasic soil physicochemical properties and enzyme activities were analyzed in the laboratory.Both in 0–20 cm and 20–40 cm soil, soil enzyme system (hydrogen peroxidase, dehydrogenase, alkaline phosphataseThe more soil enzyme activities there were, the higher the fertility of urban forest soil.
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Cofactor engineering in cyanobacteria to overcome imbalance between NADPH and NADH: A mini review

Jongmoon Park,Yunnam Choi

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 66-71 doi: 10.1007/s11705-016-1591-1

Abstract: insufficient supply of NADH, tends to limit their production yields in case of utilizing NADH-dependent enzyme

Keywords： NADH-dependent enzyme     NADPH-dependent enzyme     transhydrogenase     site-directed mutagenesis     enzyme engineering    

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Comparison between inhibitor and uncoupler for minimizing excess sludge production of an activated sludge

CHEN Guowei, XI Pengge, XU Deqian, YU Hanqing

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 1,   Pages 63-66 doi: 10.1007/s11783-007-0012-6

Abstract: minimization of excess sludge production, the reduction in the excess sludge production in the presence of an inhibitor

Keywords： uncoupling coefficient     Cu     minimization     presence     uncoupling    

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Plant diversity reduces the effect of multiple heavy metal pollution on soil enzyme activities and microbial

Yang GAO, Chiyuan MIAO, Jun XIA, Liang MAO, Yafeng WANG, Pei ZHOU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 2,   Pages 213-223 doi: 10.1007/s11783-011-0345-z

Abstract: diversity could reduce the impacts of multiple heavy metal pollution on soil microbial structure and soil enzymeSoil enzyme activity was higher in phytoremediated soil than in planted soil in this study.

Keywords： enzyme activity     soil DNA     microbial population     plant diversity     heavy metal    

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Title Author Date Type Operation

Use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in context of COVID

Jiuyang Xu, Chaolin Huang, Guohui Fan, Zhibo Liu, Lianhan Shang, Fei Zhou, Yeming Wang, Jiapei Yu, Luning Yang, Ke Xie, Zhisheng Huang, Lixue Huang, Xiaoying Gu, Hui Li, Yi Zhang, Yimin Wang, Frederick G. Hayden, Peter W. Horby, Bin Cao, Chen Wang

Journal Article

Strategies and Advances in Combating COVID-19 in China

Wei Liu, Wei-Jie Guan, Nan-Shan Zhong

Journal Article

Renin--angiotensin system inhibitor is associated with the reduced risk of all-cause mortality in COVID

Journal Article

Influence of β-elemene on the secretion of angiotensin II and expression of AT1R in hepatic stellate

Ling YANG, Rui ZHU, Qingjing ZHU, Dan DAN, Jin YE, Keshu XU, Xiaohua HOU

Journal Article

Designer enzyme for green materials innovation: Lactate-polymerizing enzyme as a key catalyst

Seiichi Taguchi

Journal Article

Power to gas: addressing renewable curtailment by converting to hydrogen

Xiaohe YAN, Xin ZHANG, Chenghong GU, Furong LI

Journal Article

Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Journal Article

Influence of glucose feeding on the ligninolytic enzyme production of the white-rot fungus Phanerochaete

ZHOU Xiaoyan, WEN Xianghua, FENG Yan

Journal Article

Diffusion process in enzyme–metal hybrid catalysts

Journal Article

Detection of Escherichia coli in wastewater based on enzyme immunoassay

XI Haiyan, CAI Qiang, HE Miao, SHI Hanchang

Journal Article

Enzyme@bismuth-ellagic acid: a versatile platform for enzyme immobilization with enhanced acid-base stability

Journal Article

Soil enzyme activities and their indication for fertility of urban forest soil

SHAN Qihua, YU Yuanchun, ZHANG Jinchi, YU Jian

Journal Article

Cofactor engineering in cyanobacteria to overcome imbalance between NADPH and NADH: A mini review

Jongmoon Park,Yunnam Choi

Journal Article

Comparison between inhibitor and uncoupler for minimizing excess sludge production of an activated sludge

CHEN Guowei, XI Pengge, XU Deqian, YU Hanqing

Journal Article

Plant diversity reduces the effect of multiple heavy metal pollution on soil enzyme activities and microbial

Yang GAO, Chiyuan MIAO, Jun XIA, Liang MAO, Yafeng WANG, Pei ZHOU

Journal Article